Formal aza-Michael additions to tropone: Addition of diverse aryl- and alkylamines to tricarbonyl(tropone)iron and [(C7H7O)Fe(CO)3]BF4 |
| |
Authors: | Zhiyuan Huang Zaki K Phelan Rachel L Tritt Shelby D Valent Daniel R Griffith |
| |
Institution: | Department of Chemistry, Lafayette College, 701 Sullivan Road, Easton, PA 18042, USA |
| |
Abstract: | A formal aza-Michael addition to tropone by way of tricarbonyl(tropone)iron and/or the tetrafluoroborate salt formed via protonation of the complex is reported. Tricarbonyl(tropone)iron smoothly undergoes the direct aza-Michael reaction with unhindered aliphatic amines under solvent free conditions in good yields. Meanwhile, the known cationic complex (C7H7O)Fe(CO)3]BF4 (whose reaction with a small number of nucleophiles was previously reported) undergoes addition with an even broader array of amine nucleophiles. Finally, it was discovered that protecting the aza-Michael adduct as a carbamate was necessary for oxidative demetallation of the complex. |
| |
Keywords: | Iron diene complexes Tropone Solvent free |
本文献已被 ScienceDirect 等数据库收录! |