Preparative synthesis of ethyl 5-acyl-4-pyrone-2-carboxylates and 6-aryl-, 6-alkyl-, and 5-acylcomanic acids on their basis |
| |
Authors: | D L Obydennov A O Goncharov V Ya Sosnovskikh |
| |
Institution: | 1.Institute of Natural Sciences of the Ural Federal University named after the first President of Russia B. N. Yeltsin,Ekaterinburg,Russian Federation |
| |
Abstract: | A simple and efficient method for the synthesis of ethyl 5-alkanoyl- and 5-aroyl-4-pyrone-2-carboxylates was developed, which is based on the condensation of 1-R-2-(dimethyl-aminomethylidene)butane-1,3-diones, obtained from 1,3-diketones and dimethylformamide dimethyl acetal, with diethyl oxalate in the presence of NaH in THF. Ethyl 5-acyl-4-pyrone-2-carboxylates were used in the synthesis of 6-R- and 5-RCO-comanic acids. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|