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Reelin expression during embryonic development of the pig brain |
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| Authors: | Karsten?B?Nielsen Annette?S?ndergaard Marianne?G?Johansen Kirsten?Schauser Morten?Vejlsted Anders?L?Nielsen Arne?L?J?rgensen Ida?E?Holm |
| Institution: | 1.Institute of Human Genetics, University of Aarhus,Aarhus C,Denmark;2.University of Copenhagen, IBHV,Frederiksberg C,Denmark;3.Department of Pathology,Aalborg Hospital, Aarhus University Hospital,Aalborg,Denmark |
| Abstract: | BackgroundReelin is an extracellular glycoprotein of crucial importance in the developmental organisation of neurons in the mammalian cerebral cortex and other laminated brain regions. The pig possesses a gyrencephalic brain that bears resemblance to the human brain. In order to establish an animal model for neuronal migration disorders in the pig, we have studied the expression pattern and structure of Reelin during pig brain development. |
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