Quantification of vestibular-induced eye movements in zebrafish larvae |
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| Authors: | Weike Mo Fangyi Chen Alex Nechiporuk and Teresa Nicolson |
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| Institution: | (1) Howard Hughes Medical Institute, Oregon Hearing Research Center and Vollum Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA;(2) Oregon Hearing Research Center, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA;(3) Department of Cellular and Developmental Biology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA |
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| Abstract: | Background Vestibular reflexes coordinate movements or sensory input with changes in body or head position. Vestibular-evoked responses
that involve the extraocular muscles include the vestibulo-ocular reflex (VOR), a compensatory eye movement to stabilize retinal
images. Although an angular VOR attributable to semicircular canal stimulation was reported to be absent in free-swimming
zebrafish larvae, recent studies reveal that vestibular-induced eye movements can be evoked in zebrafish larvae by both static
tilts and dynamic rotations that tilt the head with respect to gravity. |
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