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Selectively N‐Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self‐Assembly of Both IAPP and Aβ40 |
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| Authors: | Dr. Li‐Mei Yan Dr. Aleksandra Velkova Dipl.‐Chem. Marianna Tatarek‐Nossol Prof. Dr. Gerhard Rammes Dr. Andrei Sibaev Dr. Erika Andreetto Dipl.‐Ing. Michael Kracklauer Dipl.‐Biochem. Maria Bakou Dipl.‐Chem. Eleni Malideli Prof. Dr. Burkhard Göke Prof. Dr. Jörg Schirra Prof. Dr. Martin Storr Prof. Dr. Aphrodite Kapurniotu |
| Affiliation: | 1. Division of Peptide Biochemistry, Technische Universit?t München, Emil‐Erlenmeyer‐Forum 5, 85354 Freising (Germany) http://pbch.wzw.tum.de/;2. Institute of Biochemistry and Molecular Cell Biology, RWTH Aachen University, Aachen (Germany);3. Department of Anesthesiology, Technische Universit?t München, Klinikum Rechts der Isar, Ismaninger Strasse 22, 81675 München (Germany);4. Medizinische Klinik und Poliklinik II, Klinikum der Universit?t München‐Gro?hadern, Marchioninistrasse 15, 81377 München (Germany) |
| Abstract: | |
| Keywords: | IAPP receptor agonist islet amyloid polypeptide protein interactions self‐assembly β ‐amyloid peptide |