Palladium‐catalyzed synthesis of 8‐allyl or 8‐prenylcoumarins by using organotin reagents as multicoupling nucleophiles |
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| Authors: | Qiang Yin Han Yan Yaqin Zhang Yige Wang Guojin Zhang Yuxiang He Weihua Zhang |
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| Affiliation: | College of Science, Nanjing Agricultural University, , Nanjing, 210095 China |
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| Abstract: | In this study, 8‐iodocoumarin derivatives underwent a direct Stille cross‐coupling reaction with several organotin compounds in the presence of a catalytic amount of Pd(PPh3)4 in DMF at 80 °C. The cross‐coupling reaction proceeded smoothly under mild conditions and permitted the formation of 8‐allyl or 8‐prenylcoumarin compounds in good yields. Copyright © 2012 John Wiley & Sons, Ltd. |
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| Keywords: | palladium cross‐coupling organotin allylcoumarins prenylcoumarins |
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