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Utilizing Combinatorial Chemistry and Rational Design: Peptidic Tweezers with Nanomolar Affinity to DNA Can Be Transformed into Efficient Vectors for Gene Delivery by Addition of a Lipophilic Tail
Authors:Dr Hannes Y Kuchelmeister  Sarah Karczewski  Aljona Gutschmidt  Prof?Dr Shirley Knauer  Prof?Dr Carsten Schmuck
Institution:1. Institute for Organic Chemistry, University of Duisburg‐Essen, 45117 Essen (Germany);2. Current address: Stanford University, Department of Chemistry, Stauffer I, Stanford, CA 94305 (USA);3. Institute for Molecular Biology, University of Duisburg‐Essen, 45117 Essen (Germany)
Abstract:
Keywords:combinatorial chemistry  DNA binding  DNA transfection  DNA vectors  peptide tweezers
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