|
|||||
|
|
A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids |
|
| Authors: | Dr. Liang Xu Steven W. Plouffe Jenny Chong Prof. Dr. Jesper Wengel Prof. Dr. Dong Wang |
| Affiliation: | 1. Skaggs School of Pharmacy and Pharmaceutical Sciences, The University of California, San Diego, La Jolla, CA 92093‐0625 (USA);2. Nucleic Acid Center and Biomolecular Nanoscale Engineering Center, Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230 Odense M (Denmark) |
| Abstract: | |
| Keywords: | nucleic acid analogues RNA polymerase II sugar integrity synthetic biology transcriptional fidelity |