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Oral Disinfectants Inhibit Protein–Protein Interactions Mediated by the Anti‐Apoptotic Protein Bcl‐xL and Induce Apoptosis in Human Oral Tumor Cells
Authors:Dr. Martin Gräber  Dipl.‐Chem. Michael Hell  M. Sc. Corinna Gröst  Dr. Anders Friberg  Bianca Sperl  Prof. Dr. Michael Sattler  Prof. Dr. Thorsten Berg
Affiliation:1. Institute of Organic Chemistry, University of Leipzig, Johannisallee 29, 04103 Leipzig (Germany) http://www.uni‐leipzig.de/~tberg;2. Department of Molecular Biology, Max Planck Institute of Biochemistry, and Center for Integrated Protein Science Munich (CIPSM), Am Klopferspitz 18, 82152 Martinsried (Germany);3. Institute of Molecular Health Sciences, ETH Zurich, Schafmattstrasse 18, 8093 Zurich (Switzerland);4. Institute of Structural Biology, Helmholtz Zentrum München, Ingolst?dter Landstrasse 1, 85764 Neuherberg (Germany);5. Munich Center for Integrated Protein Science, Chair of Biomolecular NMR Spectroscopy, Department of Chemistry, Technische Universit?t München, Lichtenbergstrasse 4, 85747 Garching (Germany);6. Current address: Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232‐0146 (USA)
Abstract:
Keywords:antitumor agents  apoptosis  drug discovery  inhibitors  protein–  protein interactions
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