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Epidithiodiketopiperazine Biosynthesis: A Four‐Enzyme Cascade Converts Glutathione Conjugates into Transannular Disulfide Bridges
Authors:Dr. Daniel H. Scharf  Pranatchareeya Chankhamjon  Dr. Kirstin Scherlach  Dr. Thorsten Heinekamp  Karsten Willing  Prof. Dr. Axel A. Brakhage  Prof. Dr. Christian Hertweck
Affiliation:1. Depts. of Molecular and Applied Microbiology, Biomolecular Chemistry, and Bio Pilot Plant, Leibniz Institute for Natural Product Research and Infection Biology, HKI, Beutenbergstrasse 11a, 07745 Jena (Germany);2. Friedrich Schiller University, Jena (Germany)
Abstract:
Keywords:Aspergillus fumigatus  biosynthesis  dipeptidase  gliotoxin  mycotoxins
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