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Iron-Catalysed [3+3] Annulation of Oxime Acetates and Enaminones towards the Synthesis of Multi-Substituted Pyridines |
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| Authors: | Varaprasad Bodala Rajitha Lakshmi Podugu Kumari Yettula Dr. Padmarao Gollamudi Dr. Siddaiah Vidavalur Dr. Shyamala Pulipaka |
| Affiliation: | 1. Department of Chemistry, Andhra University, Visakhapatnam, 530003 India;2. Department of Chemistry, Dr. B. R. Ambedkar University, Srikakulam, 532410 India |
| Abstract: | A direct access to unsymmetrical and symmetrical multi-substituted pyridines has been accomplished via iron-catalysed [3+3] annulation of oxime acetates with enaminones. This protocol is featured by easily available starting materials, no requirement of expensive additives and ligands, operational simplicity, and good tolerance with diverse functional groups. |
| Keywords: | Enaminones FeCl3 Oxime acetates Substituted pyridines Terpyridine |