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A formal synthesis of (+)-lactacystin |
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| Authors: | Wardrop Duncan J Bowen Edward G |
| Affiliation: | Department of Chemistry, University of Illinois at Chicago, IL, USA. wardropd@uic.edu |
| Abstract: | A synthetic route to the neurotrophic agent (+)-lactacystin has been developed utilizing a base-promoted intramolecular alkylidenecarbene C-H insertion as the key transformation. |
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