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Chemoenzymatic Synthesis of 2-Arachidonoylglycerol, An Endogenous Ligand for Cannabinoid Receptors
Authors:Vadivel Subramanian K  Whitten Kyle M  Makriyannis A
Affiliation:Center for Drug Discovery, 116 Mugar Hall, 360 Huntington Avenue, Northeastern University, Boston, MA 02115, USA
Abstract:A simple and efficient synthesis of 2-arachidonoyl glycerol, an endogenous agonist for cannabinoid receptors was achieved using Novozym 435, immobilized lipase from Candida antarctica.
Keywords:Cannabinoid   Endogenous ligand   2-Arachidonoylglycerol   Biocatalysis
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