Emerging markers for antimicrobial resistance monitoring |
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| Institution: | 1. Liaoning & Shenyang Key Laboratory of Functional Dye and Pigment, Shenyang University of Chemical Technology, Shenyang 110142, China;2. Department of Cell Biology, China Medical University, Shenyang 110122, China;3. State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 110624, China;4. Department of Chemistry, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 7398526, Japan;1. College of Medical Imaging, Shanxi Medical University, Taiyuan 030001, China;2. College of Public Health, Shanxi Medical University, Taiyuan 030001, China;3. School of Basic Medical Science, Health Science Center, Xi''an Jiaotong University, Xi''an 710061, China;4. School of Public Health, Health Science Center, Xi''an Jiaotong University, Xi''an 710061, China;5. College of Chemistry and Life Science, Sichuan Provincial Key Laboratory for Structural Optimization and Application of Functional Molecules, Chengdu Normal University, Chengdu 611130, China;1. National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China;2. Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China;3. National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China;4. Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325000, China;1. College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China;2. State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China;1. Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China;2. Department of Chemistry, Taiyuan Normal University, Jinzhong 030619, China;3. Department of Electronic Science, Xiamen University, Xiamen 361005, China |
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| Abstract: | The appearance and spread of antibiotic-resistant pathogens known as antimicrobial resistance (AMR) is one of the major worldwide health crises that humanity have to deal with over the next decades. One of the main methods for addressing AMR is the effective screening for antimicrobial insensitivity in clinical and environmental monitoring. Current clinical laboratory procedures use traditional culture-based antibiotic susceptibility testing (AST) methods, which can take up to 24 h to identify which drug is suitable for the infection inhibition. Therefore, it is vital to develop novel strategies that offer quick, simple, affordable, reliable, sensitive and accurate AMR monitoring. Sensors for AMR markers detection could possess the essential qualities for quickly identifying resistant microorganisms and could give vital data for the selection of antibacterial drugs administration. This review offers a summary of the innovative application of these AMR markers detection strategies focusing on healthcare and environmental surveillance for the AMR genotypic or phenotypic assessment. |
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