Synthesis and conversions of 2-aryl derivatives of s-triazolo[4,3-a]pyrimidine |
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Authors: | I. Krezhel' |
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Affiliation: | (1) Department of Pharmaceutics, Lodz Academy of Medicine, 90-145 Lodz, Poland |
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Abstract: | The reaction of arylhydrazines and 1-ethoxycarbonyl-2-methylthio-1,4,5,6-tetrahydropyrimidines forms 2-aryl-3-oxo-2,3,5,6,7,8-hexahydro-s-triazolo[4,3-a]pyrimidines. The reaction of 2-phenyl substituted triazolo[4,3-a]pyrimidine with various acylating agents to give 8-acyl derivatives and the effect thereon of hydrogen chloride were studied. The amine-imine tautomerism of these compounds was studied by PMR spectroscopy.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1350–1353, October, 1986. |
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