A simple and rapid protocol for the synthesis of phenacyl derivatives using macroporous polymer-supported reagents |
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| Authors: | Ali R Kiasat and Soheil Sayyahi |
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| Institution: | (1) Innovative Technology Center (ACS), Department of Chemistry, University of Cambridge, Cambridge, CB21EW, UK; |
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| Abstract: | This article describes the use of Amberlite IRA-910 with different counter ions as excellent polymer-supported reagents in
nucleophilic substitution reactions. The versatility of this protocol allowed the synthesis of a diversified library of phenacyl
derivatives with high yields. The polymeric reagents can be reloaded several times with no loss of their efficiency. |
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