取代二苯醚的新合成反应及历程研究

在碱金属亚硝酸盐和碳酸盐存在下, 被强引电子基团取代的硝基苯在非质子极性溶剂中能发生自射缩合反应, 生成结构对称的双取代二苯醚, 收率较高。此类反应的主要历程属于SNAr, 但同时也存在着SRNAr(SET)历程作为次要途径。

Investigation on the new synthetic reactions and mechanisms of substituted diphenyl ethers

In the present of alkali nitrite and carbonate, some nitrobenzenes substituted by strongly electron withdrawing groups undergo a self condensation in an aprotic polar solvent to give symmetrical disubstituted diphenyl ethers in good yields. a possible mechanism is discussed ,the nucleophili aromatic substitution SNAr and ARNAr (SET)may occur simultaneouly.