The determination of trace amounts of chlorophenols by high-performance liquid chromatography

A method is given for the separation and determination of eight chlorophenols using HPLC. The chlorophenols after extraction from aqueous solution by means of diethyl ether are taken up in a 1% methanol-petroleum spirit mixture and injected onto the column. Separation of a mixture of all eight chlorophenols can be achieved in 25 min and a linear relationship exists for each chlorophenol for concentrations in the range 0.1–1.0 ppm.