Remote stereocontrol by sulfinyl groups: reduction of delta-ketosulfoxides |
| |
| Authors: | García Ruano José L Fernández-Ibáñez M Angeles Maestro M Carmen Rodríguez-Fernández M Mercedes |
| |
| Affiliation: | Departamento de Química Orgánica, Universidad Autónoma de Madrid, Cantoblanco, 28049-Madrid, Spain. joseluis.garcia.ruano@uam.es |
| |
| Abstract: | The reduction of delta-ketosulfoxides constitutes the first evidence of the efficiency of the sulfinyl group to control the stereoselectivity of 1,5-asymmetric induction processes. The use of DIBAL/Yb(OTf)3 or L-Selectride as the reducing agents provides delta-hydroxysulfoxides with the opposite configuration at the hydroxylic carbon in a highly stereoselective way. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
