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An expeditious chiral route to analogs of mevinolin and compactin |
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| Authors: | Ta-Jyh Lee |
| Affiliation: | Department of Medicinal Chemistry Merck Sharp & Dohme Research Laboratories, West Point, Pennsylvania 19486 U.S.A. |
| Abstract: | A new and novel approach to the preparation of optically active analogs of mevinolin and compactin, in which the β-hydroxy-δ-lactone moiety is derived from D-glucose, is described. |
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