Total synthesis of (+)-castanospermine from D-mannose |
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Authors: | Hiroyuki Setoi Hidekazu Takeno Masashi Hashimoto |
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Affiliation: | Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd. 2-1-6 Kashima, Yodogawa-ku, Osaka 532, Japan |
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Abstract: | A total synthesis of (+)-castanospermine (2) has been achieved starting from D-mannose by a route adopting a double-cyclization process (5c→6) as the key step. |
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