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The trapping of sulfenic acids from penicillin sulfoxides - use of 2,5-dimercapto-1,3,4-thiadiazole and 2,4-dimercaptopyrimidine as trapping agents.
Authors:Ronald G Micetich  Samarendra N Maiti  Maya P Singh  M Tanaka  T Yamazaki  K Ogawa
Institution:1. Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada, T6G 2N8.;2. Research Institute, Taiho Pharmaceutical Company Limited, Tokushima, Japan.
Abstract:2,5-Dimercapto-1,3,4-thiadiazole and 2,4-dimercaptopyrimidine were used to trap sulfenic acids from penicillin sulfoxides.
Keywords:
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