Syntheses of all four possible diastereomers of the acyclonucleoside 9-(1,3,4-trihydroxy-2-butoxymethyl)guanine from carbohydrate precursors |
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Authors: | Malcolm MacCoss Anna Chen Richard L. Tolman |
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Affiliation: | Merck Sharp and Dohme Research Laboratories, P.O. Box 2000 Rahway, New Jersey 07065 U.S.A. |
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Abstract: | The syntheses of all four possible diastereomers of 9-(1,3,4-trihydroxy-2-butoxymethyl)guanine, starting from D- and L-xylose and from D- and L-arabinose derivatives are described. |
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