Synthesis of 4-substituted glutarimides by free radical addition of iodoacetamide to α,β-unsaturated esters |
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| Authors: | Guerino Sacripante Charles Tan George Just |
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| Institution: | Department of Chemistry, McGill University Montreal, Canada H3A 2K6 |
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| Abstract: | Free radical addition of either methyl bromoacetate or iodoacetamide to an α,β,-unsaturated ester gave the 4-substituted glutarate or glutarimide respectively, whereas the radical cyclisation of N-bromoacetyl crotonamide gave the 2-substituted succinimide. |
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