The application of highly stereoselective aldol condensations to the synthesis of β-lactam antibiotics. |
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| Authors: | Mankil Jung Marvin J. Miller |
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| Affiliation: | Department of Chemistry, University of Notre Dame, Notre Dame, IN 46556 U.S.A. |
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| Abstract: | Stereoselective aldol condensations of fully protected glycine and 3-butyryl thiazolidine-2-thiones with achiral aldehydes afforded β-hydroxyesters suitable for elaboration to key intermediates for the synthesis of β-lactam antibiotics. |
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