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An efficient diastereoselective synthesis of 6-hydroxy-4a-[3,4-crowned(15-crown-5)phenyl]-trans-decahydroisoquinoline
Authors:Shinzo Kano  Tsutomu Yokomatsu  Hajime Nemoto  Shiroshi Shibuya
Institution:Tokyo College of Pharmacy, 1432-1 Horinouchi, Hachioji, Tokyo 192-03, Japan
Abstract:A high diastereoselective synthesis of 6-hydroxy-4a-aryl-trans-decahydroisoquinoline derivatives was achieved by an application of N-acyliminium ion-induced polyene cyclization procedure.
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