Reactivite du tris(hydroxymethyl)aminomethane avec des nitro-aldehydes aromatiques. Synthese de nouveaux composes antimicrobiens. |
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| Authors: | Robert Nouguier Michel Crozet Patrice Vanelle José Maldonado |
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| Institution: | Laboratoire de Chimie Organique B, CNSR UA 109, Faculté des Sciences de St Jéromé, rue H. Poincaré, 13397 Marseille Cedex 13 France.;Laboratoire de Chimie Organique, Faculté de Pharmacie, 27 Bd J. Moulin 13885 Marseille Cedex 4. France |
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| Abstract: | Heterogeneous reaction of TRIS 1 with nitro-aldehydes leads to oxazolidines in good yield. New products are obtained as monocyclic or bicyclic compounds, and are of potential medicinal value. |
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