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Ratiometric Single‐Nanoparticle Oxygen Sensors for Biological Imaging
Authors:Changfeng Wu  Barbara Bull  Kenneth Christensen Prof  Jason McNeill Prof
Institution:Department of Chemistry, Clemson University, Clemson, SC 29634 (USA), Fax: (+1) 864‐656‐6613
Abstract:It makes sense : Conjugated polymer nanoparticles doped with a platinum porphyrin dye exhibit bright phosphorescence that is highly sensitive to the concentration of molecular oxygen. The small size, extraordinary brightness, excellent sensitivity, and ratiometric emission, together with the demonstration of single‐particle sensing and cellular uptake, indicate the potential of the nanoparticle sensors for quantitative mapping of local molecular oxygen concentration.
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Keywords:fluorescent probes  FRET  nanostructures  polymers  sensors
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