Preparation of novel axially chiral NHC–Pd(II) complexes and their application in oxidative kinetic resolution of secondary alcohols |
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| Authors: | Shi‐Jia Liu Lian‐jun Liu Min Shi |
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| Institution: | 1. Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, People's Republic of China;2. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, People's Republic of China |
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| Abstract: | Novel axially chiral N‐heterocyclic carbene (NHC) Pd(II) complexes were prepared from optically active 1,1′‐binaphthalenyl‐2,2′‐diamine (BINAM) and H8‐BINAM and their crystal structures were unambiguously determined by X‐ray diffraction. These chiral N‐heterocyclic carbene (NHC) Pd(II) complexes were applied in the oxidative kinetic resolution of secondary alcohols using molecular oxygen as a terminal oxidant or under aerobic conditions, affording the corresponding sec‐alcohols in good yields with moderate to good enantioselectivities. Copyright © 2009 John Wiley & Sons, Ltd. |
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| Keywords: | axially chiral NHC‐Pd(II) complex 1 1′ ‐binaphthalenyl‐2 2′ ‐diamine (BINAM) H8‐BINAM X‐ray diffraction oxidative kinetic resolution of secondary alcohols |
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