|
|||||
|
|
A Powerful Chiral Counteranion Motif for Asymmetric Catalysis |
|
| Authors: | Pilar García‐García Dr. Frank Lay Patricia García‐García Dr. Constantinos Rabalakos Dr. Benjamin List Prof. Dr. |
| Affiliation: | 1. Max‐Planck‐Institut für Kohlenforschung, Kaiser‐Wilhelm‐Platz 1, 45470 Mülheim an der Ruhr (Germany), Fax: (+49)?208‐306‐2999;2. These authors contributed equally. |
| Abstract: | Room to swing a cat : A chiral disulfonimide has been designed as a powerful new motif for asymmetric catalysis. As a first illustration, a highly efficient and enantioselective Mukaiyama aldol reaction has been developed (see scheme). The actual catalyst is proposed to be an N‐silyl imide which is generated in situ.  |
| Keywords: | disulfonimides homogeneous catalysis Mukaiyama aldol reaction organocatalysis |