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pH‐Dependent Optical Properties of Synthetic Fluorescent Imidazoles |
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| Authors: | Mikhail Y Berezin Dr Jeff Kao Dr Samuel Achilefu Prof Dr |
| Institution: | 1. Department of Radiology, Washington University School of Medicine, 4525 Scott Avenue, St. Louis, MO 63110 (USA), Fax: (+1)?314‐747‐5191, Homepage: http:/www/orl.wustl.edu;2. Department of Chemistry, Washington University, St. Louis, MO 63130 (USA);3. Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110 (USA) |
| Abstract: | New pH‐sensitive probe design : A peek into the structure of fluorescent proteins led to the synthesis of fluorescent imidazoles. The prepared compounds demonstrated an array of remarkable pH‐dependent optical properties including at least two types of excited‐state charge transfers (see picture).  |
| Keywords: | charge transfer emission spectroscopy energy transfer imidazole pH sensitivity sensors |