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In Situ Enamine Activation in Aqueous Salt Solutions: Highly Efficient Asymmetric Organocatalytic Diels–Alder Reaction of Cyclohexenones with Nitroolefins |
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| Authors: | Dan‐Qian Xu Ai‐Bao Xia Shu‐Ping Luo Jie Tang Shuai Zhang Jun‐Rong Jiang Zhen‐Yuan Xu |
| Institution: | State Key Laboratory Breeding Base of Green Chemistry‐Synthesis Technology, Zhejiang University of Technology, Hangzhou (China), Fax: (+86)?571‐8832‐0066 |
| Abstract: | Deep‐sea Diels–Alder : The asymmetric organocatalytic Diels–Alder reaction of cyclohexenones with aromatic nitroolefins can be carried out in seawater and brine. The reaction proceeds by an in situ enamine activation involving a one‐step concerted addition pathway (see scheme).  |
| Keywords: | asymmetric catalysis bicyclic systems Diels– Alder reaction organocatalysis water chemistry |