Cell Dynamics Research Center, Research Center for Biomolecular Nanotechnology, Department of Life Science, Gwangju Institute of Science and Technology (GIST), 1 Oryong‐dong, Gwangju 500‐712 (South Korea), Fax: (+82)?62‐970‐2504
Abstract:
Seeing is sensing : Calsequestrin (CSQ) functionalized gold nanoparticles undergo calcium‐dependent CSQ polymerization, which results in a clear color change (see picture) together with precipitation. The sensing system is specific for Ca2+ ions and the differences between normal and disease‐associated abnormal (hypercalcemia) Ca2+ ion levels in serum can be distinguished with the naked eye.
