Department of Chemistry, University of Arkansas at Little Rock, 2801 South University Avenue, Little Rock, AR 72204 (USA), Fax: (+1)?501‐569‐8838 http://www.ualr.edu/wxzhao
Abstract:
A cunning plan : In the multifunctional fluorescent probe MitoPY1 the phosphonium head group (red) targets mitochondria and the boronate group (green) responds to hydrogen peroxide. MitoPY1 reacts selectively with mitochondrial H2O2 in living cells, and an increase in fluorescence is triggered by the conversion of MitoPY1 into MitoPY1ox (yellow).