1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7‐3‐1, Hongo, Bunkyo‐ku, Tokyo 113‐0033 (Japan), Fax: (+81)?3‐5841‐4735;2. Advanced Elements Chemistry Laboratory, The Institute of Physical and Chemical Research (RIKEN), Wako‐shi, Saitama 351‐0198 (Japan), Fax: (+81)?48‐467‐2879
Abstract:
Density functional theory and fragment‐energy analysis have been used to probe the mechanism of the halogen–zinc exchange reaction. In their Full Paper on page 5686 ff. , M. Uchiyama, S. Nakamura et al. discuss three important factors in this reaction: The effect of the halogen species, the effect of the alkyl ligand on zinc, and the effect of the substrate nature.
