Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave, Rm 18‐492 (USA), Fax: 1‐617‐324‐0253
Abstract:
Extension ladder : The successful application of epoxide‐opening strategies towards the synthesis of ladder‐type polyethers is contingent upon further elaboration of the product. By employing two different functionalized templates, a fragment of gymnocin A that bears four sites for subsequent fragment coupling has been prepared (see scheme; Bn=benzyl).