1. Department of Chemistry, The Scripps Research Institute, 10650 N. Torrey Pines Road, La Jolla, CA 92037 (USA);2. Fachbereich Chemie der Philipps Universit?t, 35032 Marburg (Germany)
Abstract:
Stimulus package for organic synthesis : The economy of step and atom usage has been widely reviewed and acknowledged as being useful frameworks to evaluate the efficiency of synthesis. This Review brings to attention another form of economy which should be considered in the planning and evaluation of a multistep synthesis: redox economy. Several guidelines and examples are included to illustrate the logic of this approach and to stimulate the design of syntheses.