A one‐pot,stereoselective synthesis of 2‐ethoxycarbonyl‐substituted 1,3‐dienes and 1,3‐enynes by hydrostannylation–Stille tandem reaction of tributyltin hydride with alkynyl esters and alkenyl or alkynyl halides |
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| Authors: | Mingzhong Cai Xiaoniu Fang Ruchun Dai Lingfang Zha |
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| Institution: | 1. School of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, People's Republic of China;2. School of Chemistry and Chemical Engineering, Jinggangshan University, Jian 343009, People's Republic of China |
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| Abstract: | 2‐Ethoxycarbonyl‐substituted 1,3‐dienes and 1,3‐enynes can be stereoselectively synthesized in one pot under mild conditions, in good yields, by the palladium‐catalyzed hydrostannylation of alkynyl esters, followed by Stille coupling with alkenyl or alkynyl halides, respectively. Copyright © 2009 John Wiley & Sons, Ltd. |
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| Keywords: | hydrostannylation (E)‐α ‐stannyl‐α β ‐unsaturated esters Stille coupling 1 3‐diene 1 3‐enyne |
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