Department of Chemistry, Gakushuin University, 1‐5‐1, Mejiro, Toshima‐ku, Tokyo 171‐8588 (Japan), Fax: (+81)?3‐5992‐1029
Abstract:
Let′s resolve our differences : Implementation of an enantioselective Michael addition followed by an intramolecular aldol reaction catalyzed by two phosphoric acids has enabled the synthesis of cyclohexenone derivatives with excellent enantioselectivities. Prominent kinetic resolution was observed in the latter reaction. Ar=aromatic group, X=H, halogen, Y=H, Me, halogen.