Multiresidue analysis of 47 pesticides in cooked wheat flour and polished rice by liquid chromatography with tandem mass spectrometry |
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| Authors: | Sung Jung Lee Hyeong Jin Park Wooseong Kim Jong Sung Jin A. M. Abd El‐Aty Jae‐Han Shim Sung Chul Shin |
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| Affiliation: | 1. Department of Chemistry and Research Institute of Life Science, Gyeongsang National University, Jinju, 660‐701, Republic of Korea;2. Busan Regional Korea Food and Drug Administration, 123‐7 Yong‐Dong Dong Nam‐Ku Busan, Republic of Korea;3. Korea Basic Science Institute Busan Center, High Technique Components and Materials Team, Gangseo‐gu, Busan, 618‐230, Republic of Korea;4. Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Konkuk University, 1 Hwayang‐dong, Kwangjin‐gu, Seoul 143‐701, Republic of Korea;5. Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, 12211‐Giza, Egypt;6. Natural Products Chemistry Laboratory, Institute of Agricultural Science and Technology, College of Agriculture and Life Science, Chonnam National University, 300 Yong‐Bong Dong, Buk‐Ku, Gwangju 500‐757, Republic of Korea |
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| Abstract: | Liquid chromatography in conjunction with tandem mass spectrometry was used to directly quantify of 47 pesticide residues from cooked wheat flour and polished rice, which are the most widely consumed cereals in the Republic of Korea. The sample clean‐up was carried out according to the method established by the Korea Food and Drug Administration. The mobile phase for liquid chromatograpy separation consisted of water and 5 mm methanolic ammonium formate. Tandem mass spectroscopy experiments were performed in electrospray ionization positive mode and the multiple reaction monitoring mode. The matrix effects estimated for the 47 pesticides had a mean value of 99% and ranged from 45 to 147%. High recoveries (70–140%) and relative standard deviations (≤20%) were achieved for most of the pesticides tested. The method used in this study allowed for rapid quantification and identification of low levels of pesticides in cooked wheat flour and polished rice samples. Of the screened pesticide residues, only tricyclazole and fenobucarb were found in polished rice samples. However, no samples contained residues above the MRL established by the Korea Food and Drug Administration. Copyright © 2008 John Wiley & Sons, Ltd. |
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| Keywords: | tandem mass spectrometry pesticide residues validation multiresidue bioanalytical application |
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