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A Supramolecular Polymer as a Self‐Assembling Polyvalent Scaffold |
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| Authors: | Marion K. Müller Luc Brunsveld Prof. Dr. |
| Affiliation: | 1. Department of Chemical Biology, Max Planck Institute for Molecular Physiology and Chemical Genomics Centre, Otto‐Hahn‐Strasse 15, 44227 Dortmund (Germany);2. Laboratory of Chemical Biology, Department of Biomedical Engineering, TU Eindhoven, Eindhoven (The Netherlands), Fax: (+31)?40‐247‐8367, http://www.bmt.tue.nl/cb |
| Abstract: | Binding bacteria : Discotic molecules self‐assemble into columnar supramolecular polymers that show strong polyvalent binding to bacteria by virtue of mannose ligands attached at their periphery (orange; see picture). The reversible formation of the supramolecular polymers allows simple mixing of differently substituted monomers and the optimization of bacterial aggregation.  |
| Keywords: | carbohydrates fluorescence polyvalency self‐assembly supramolecular polymers |