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Protein‐Functionalized Synthetic Antiferromagnetic Nanoparticles for Biomolecule Detection and Magnetic Manipulation |
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| Authors: | Aihua Fu Dr Wei Hu Liang Xu Robert J Wilson Dr Heng Yu Dr Sebastian J Osterfeld Sanjiv S Gambhir Prof Shan X Wang Prof |
| Institution: | 1. Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305 (USA);2. Departments of Radiology and Bioengineering, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305 (USA) |
| Abstract: | Direct protein functionalization provides synthetic antiferromagnetic nanoparticles with high chemical specificity and multifunctionality. These nanoparticle–protein conjugates function as improved magnetic labels for biological detection experiments, and exhibit tunable responses to a small external magnetic field gradient, thus allowing the observation of distinctive single nanoparticle motion.  |
| Keywords: | biosensors magnetic properties nanotechnology single particle manipulation surface functionalization |