Continuous Separation of Racemic 3,5‐Dinitrobenzoyl‐Amino Acids in a Centrifugal Contact Separator with the Aid of Cinchona‐Based Chiral Host Compounds
Resolution through revolution : It is possible to extract 3,5‐dinitrobenzoyl‐protected amino acids enantioselectively with the aid of a table‐top centrifugal contact separator and a catalytic amount of a chiral host compound based on the Cinchona alkaloids. Enantioselectivities of up to 80 % could be reached in a single pass. This allows the development of a process for the continuous separation of racemates.