Instituto de Química Orgánica General, C.S.I.C. Juan de la Cierva 3, 28006 Madrid (Spain), Fax: (+34)?915‐644‐853
Abstract:
Highly diastereoselective Claisen rearrangements of acyclic allyl vinyl ethers bearing a chiral sulfoxide at C‐5 provide γ‐δ‐unsaturated aldehydes or ketones with up to two consecutive asymmetric centers in the molecule whilst preserving a useful vinyl sulfoxide. The reactivity of related vinyl sulfides and sulfones has also been examined in this work.