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Synthesis of Unprecedented Scaffold Diversity |
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| Authors: | Warren R J D Galloway Mónica Diáz‐Gavilán Dr Albert Isidro‐Llobet Dr David R Spring Dr |
| Institution: | Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK), Fax: (+44)?1223‐336‐362 http://www‐spring.ch.cam.ac.uk/ |
| Abstract: | Building a better library : The synthesis of a library of natural‐product‐like small molecules with unprecedented scaffold diversity has been reported (see scheme; Ns=nosylate). The library represents a significant advancement in the capability of synthetic chemists to generate structurally diverse and complex small molecules in a rapid manner.  |
| Keywords: | combinatorial chemistry diversity‐oriented synthesis metathesis molecular scaffolds natural products |