Hydrodebromination of bromoarenes using Grignard reagents catalyzed by metal ions |
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| Authors: | Miao Shen Wen‐Hua Sun |
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| Affiliation: | 1. Key Laboratory of Engineering Plastics and Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, People's Republic of China;2. State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, People's Republic of China |
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| Abstract: | The metal salts, FeCl·24H2O, FeCl3, NiCl2, CoCl2, CuBr and some iron complexes were found to be efficient catalysts for hydrodebromination of bromoarenes under mild reaction conditions with two equivalents of Grignard reagents. Among them, the iron systems showed the best behavior regarding economic and environmental considerations. All the alkyl Grignard reagents (except CH3MgCl) and p‐tolylMgBr were promising reductive reagents with the formation of their homo‐coupling products. Copyright © 2008 John Wiley & Sons, Ltd. |
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| Keywords: | hydrodebromination metal salts/complexes Grignard reagent bromoarenes |
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