University of Texas at Austin, Department of Chemistry and Biochemistry, 1 University Station—A5300, Austin, TX 78712‐1167 (USA), Fax: (+1)?512‐471‐8696
Abstract:
Unstable? We're able! 1,n‐Glycols serve as synthetic equivalents to unstable dialdehydes in two‐directional carbonyl allylation from the alcohol oxidation level under iridium‐catalyzed transfer hydrogenation conditions. Iterative asymmetric allylation employing 1,3‐propanediol enables the rapid assembly of protected 1,3‐polyol substructures with exceptional levels of stereocontrol.
