Institut des Biomolécules Max Mousseron (IBMM), UMR 5247CNRS‐Universités Montpellier 2 et 1, Batiment de Recherche Max Mousseron, Ecole Nationale Supérieure de Chimie de Montpellier, 8, rue de l'Ecole Normale, 34296 Montpellier Cedex 5 (France), Fax: (+33)?467‐14‐43‐44
Abstract:
A domino effect from one extremity to the other is observed in a large‐amplitude mannosyl 2]rotaxane molecular machine. In their Communication on page 5186 ff., F. Coutrot and E. Busseron describe the efficient preparation of new 2]rotaxane molecular machines containing anilinium and either mono‐ or disubstituted pyridinium amide stations. In the case of the disubstituted pyridinium amide, the macrocycle shuttles from the anilinium to the pyridinium upon deprotonation and causes an impressive flipping of the chair conformation of the glucidic moiety.
