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A New Two‐Photon‐Sensitive Block Copolymer Nanocarrier
Authors:Jérôme Babin Dr.  Maxime Pelletier  Martin Lepage Prof. Dr.  Jean‐François Allard  Denis Morris Prof. Dr.  Yue Zhao Prof. Dr.
Affiliation:1. Département de chimie, Université de Sherbrooke, Sherbrooke, Québec, J1K2R1 (Canada), Fax: (+1)?819‐821‐8017, http://pages.usherbrooke.ca/yzhao/;2. Département de médecine nucléaire et de radiobiologie and Centre d'imagerie moléculaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, Québec, J1K2R1 (Canada);3. Département de physique, Université de Sherbrooke, Sherbrooke, Québec, J1K2R1 (Canada)
Abstract:Easily disrupted : Micelles of a new amphiphilic block copolymer that bear coumarin groups are sensitive to near infrared light by two‐photon absorption of the chromophore. Disruption of the micelles under irradiation at 794 nm results in release of both photocleaved coumarin and encapsulated nile red from the hydrophobic core of micelle into aqueous solution, which results in opposing changes in fluorescence emission intensity.
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Keywords:block copolymers  dyes and pigments  micelles  photochemistry  photocontrollable release
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