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Asymmetric Synthesis of Anisodine
作者姓名:Yan  Fen  WU  Wen  LUE  Qiang  LU  Wen  Sheng  ZHANG
作者单位:School of Pharmaceutical Sciences, Peking University, Beijing 100083
摘    要:Anisodine was synthesized from 3α-hydroxy-6β-acetyltropine in 11 steps. Laevorotary isomer of anisodine was prepared from the asymmetric dihydroxylation of compound 10 via the osmium catalyzed process employing p-chlorobenzoyl dihydroquinidine as the chiral ligands.

关 键 词:托品碱  生物碱  不对称合成  药理活性
收稿时间:2004-12-20

Asymmetric Synthesis of Anisodine
Yan Fen WU Wen LUE Qiang LU Wen Sheng ZHANG.Asymmetric Synthesis of Anisodine[J].Chinese Chemical Letters,2005,16(10):1287-1289.
Authors:Yan;Fen;WU;Wen;LUE;Qiang;LU;Wen;Sheng;ZHANG
Abstract:
Keywords:Anisodine  tropine alkaloid  total synthesis  
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